Coumarins and derivatives
Apexbio Technology LLC 6-METHYLCOUMARIN-100MG
6-Methylcoumarin (CAS No 92-48-8) is a compound used primarily in biomedical research focusing on its potential therapeutic properties It is derived from the coumarin family of aromatic organic compounds The mechanism of action often involves modulating enzymatic pathways and interacting with cellular receptors that influence various biological processes In vitro 6-Methylcoumarin exhibits activity generally within the nanomolar to low micromolar range making it a candidate for studies on enzyme inhibition and receptor binding It is commonly applied in cell models and animal studies to explore anti-inflammatory antimicrobial or anticancer effects This compound is also used in drug screening processes to evaluate pharmacological profiles under various experimental conditions Experimental concentrations typically depend on the specific research design ensuring that results are relevant to the intended application
Apexbio Technology LLC 6-METHYLCOUMARIN-200MG
6-Methylcoumarin (CAS No 92-48-8) is a compound used primarily in biomedical research focusing on its potential therapeutic properties It is derived from the coumarin family of aromatic organic compounds The mechanism of action often involves modulating enzymatic pathways and interacting with cellular receptors that influence various biological processes In vitro 6-Methylcoumarin exhibits activity generally within the nanomolar to low micromolar range making it a candidate for studies on enzyme inhibition and receptor binding It is commonly applied in cell models and animal studies to explore anti-inflammatory antimicrobial or anticancer effects This compound is also used in drug screening processes to evaluate pharmacological profiles under various experimental conditions Experimental concentrations typically depend on the specific research design ensuring that results are relevant to the intended application
Apexbio Technology LLC MY-1076-50MG
MY-1076 (CAS No 3008262-76-5) is a compound frequently used in biomedical research focusing on cellular pathways and targeted therapies It acts by modulating specific molecular targets involved in various signaling cascades Commonly it demonstrates in vitro activity in the nanomolar to low micromolar range which suggests significant potency Typical applications include studies using cell models and animal subjects for investigating therapeutic effects or potential drug development It is often utilized in drug screening assays to evaluate efficacy across different experimental conditions Experimental concentrations typically depend on the specific research design
Medchemexpress LLC 6-Methylcoumarin | 92-48-8 | 160.17 | 1 ML
6-Methylcoumarin is a synthetic fragrance primarily used in cosmetics. It has been reported to be almost nonphototoxic in epidermal tissue and cell culture phototoxicity test models. Studies show that when HaCaT cells are treated with 6-Methylcoumarin and UVA irradiation, it produces γ-H2AX-positive cells at concentrations from 100 nM.
- Synthetic fragrance widely used in cosmetics.
- Reported to be almost nonphototoxic in epidermal tissue and cell culture phototoxicity test models.
Medchemexpress LLC 7-Methylcoumarin | 2445-83-2 | 50 G
7-Methylcoumarin is a coumarin derivative with potent hepatoprotective and antioxidant properties. It acts as a mechanism-based inhibitor for CYP2A6. This compound has been shown to significantly decrease alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB) in rats with CCl4-induced liver damage, while also restoring total protein (TP) and albumin (TA) levels in serum and preventing oxidative stress. Additionally, 7-Methylcoumarin can reduce the mitotic activity of *A. sativum* promeristem.
- Potent hepatoprotective properties.
- Antioxidant properties.
- Mechanism-based inhibitor for CYP2A6.
- Decreases ALT, AST, and serum bilirubin in rats with CCl4-induced liver damage.
- Restores total protein and albumin levels in serum.
- Prevents oxidative stress.
- Can decline mitotic activity of *A. sativum* promeristem.
Cayman Chemical 3-HydroxycoumarIn 5g
A coumarin with diverse biological activities; inhibits 15-LO-1 (IC50 = 9.5 µM); scavenges DPPH radicals in a cell-free assay (IC50 = 0.61 mM); inhibits lipid peroxidation in vitro (IC50 = 69.07 mM); protective against UVB-induced embryotoxicity in sea urchins
Chem-Impex International, Inc. Umbelliferone | 93-35-6 | MFCD00006878 | 100G
Umbelliferone, 93-35-6, MFCD00006878, 100G
Medchemexpress LLC 6-Hydroxycoumarin | 6093-68-1 | MFCD00630040 | 500 MG
6-Hydroxycoumarin is a coumarin that exhibits a range of biological activities. It is intended for research use only.
- Anti-inflammatory properties
- Anti-pyretic properties
- Anti-oxidant properties
- Vasodilator properties
- Anti-amoebic properties
- Anti-bacterial properties
- Anti-fungal properties
- Bacteriostatic properties
- Antitumor properties
Medchemexpress LLC 3-Hydroxycoumarin | 939-19-5 | 99.3% | 50 MG
3-Hydroxycoumarin is an inhibitor of tyrosinase and lipoxygenase (LOX), with an IC50 for recombinant human tyrosinase (rHT) of 26 μM and an IC50 for LOX of 9.5 μM. It exhibits DPPH free radical scavenging activity and has photoprotective effects on sea urchin zygotes and embryos. The compound has also demonstrated anticancer activity against human SK-MEL-28 cells and SK-MEL3 cells in vitro.
- Inhibits tyrosinase and lipoxygenase
- Exhibits DPPH free radical scavenging activity
- Provides photoprotective effects on sea urchin zygotes and embryos
- Shows anticancer activity against human SK-MEL-28 and SK-MEL3 cells
- Can be formulated into a vesicle delivery system for topical administration
Medchemexpress LLC 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester | 134471-24-2 | MFCD00037568 | ≥95.0% | 5 MG
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. It is a blue fluorescent dye for labeling proteins and nucleic acids.
- Fluorescent dye
- Amine-reactive succinimidyl ester
- Labels proteins and nucleic acids
Medchemexpress LLC 6-Hydroxycoumarin | 6093-68-1 | 10 G
6-Hydroxycoumarin is a coumarin exhibiting diverse biological activities. It is noted for its anti-inflammatory, anti-pyretic, anti-oxidant, and vasodilator properties. This compound also demonstrates anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic, and antitumor activities.
- Demonstrates anti-inflammatory, anti-pyretic, and anti-oxidant activities
- Acts as a vasodilator, anti-amoebic, anti-bacterial, and anti-fungal agent
- Exhibits bacteriostatic and antitumor properties
- Appearance: light yellow to light brown solid
- Molecular formula: C9H6O3
- Molecular weight: 162.14
- Purity: 99.32%
- Melting point: 249-253 °C
- Boiling point: 248.82 °C at 760 mmHg